Vascular Inflammation Evaluated by [18F]-Fluorodeoxyglucose Positron Emission Tomography Is Associated With the Metabolic Syndrome
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چکیده
منابع مشابه
Vascular Inflammation Evaluated by [18F]-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography Is Associated With Endothelial Dysfunction.
OBJECTIVE Endothelial dysfunction is an initial step in atherosclerotic cardiovascular disease. However, involvement of vascular inflammation in endothelial dysfunction is not fully investigated in humans because of the lack of diagnostic modality to noninvasively evaluate vascular inflammation. We assessed the relationship between endothelial function and vascular inflammation evaluated by [(1...
متن کاملImaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography.
BACKGROUND Atherosclerotic plaque rupture is usually a consequence of inflammatory cell activity within the plaque. Current imaging techniques provide anatomic data but no indication of plaque inflammation. The glucose analogue [18F]-fluorodeoxyglucose (18FDG) can be used to image inflammatory cell activity non-invasively by PET. In this study we tested whether 18FDG-PET imaging can identify in...
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Atherosclerosis remains the leading cause of death in North America and Europe. During the natural course of atherosclerosis, inflammation plays a major role in the development of complex plaque lesions containing activated macrophages, foam cells, T lymphocytes, mast cells, and a necrotic lipid-rich core (1). When such a plaque becomes unstable due to uncontrolled inflammation and thinning of ...
متن کاملVascular Imaging With 18F-Fluorodeoxyglucose Positron Emission Tomography Is Influenced by Hypoxia
Vascular imaging with 18 F-fluorodeoxyglucose posi-tron emission tomography (18 FDG-PET) provides a noninvasive surrogate of inflammation and has been used to test novel drug treatments for atherosclerosis (1). Hypoxia exists in atherosclerosis (2) and may contribute to the measured FDG signal (3). 18 F-fluo-romisonidazole (FMISO) PET can quantify hypoxia in tumors; it has not been applied to h...
متن کاملAssociation of adiponectin, resistin, and vascular inflammation: analysis with 18F-fluorodeoxyglucose positron emission tomography.
OBJECTIVE Adiponectin and resistin are adipokines that are linked to obesity, inflammation, and atherosclerosis. (18)F-Fluorodeoxyglucose (FDG) positron emission tomography is a promising imaging technique that can be used to evaluate vascular inflammation. METHODS AND RESULTS We measured adiponectin and resistin levels, as well as traditional cardiovascular risk factors, in 60 obese subjects...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2007
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2006.11.046